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|---|---|
| Accession Number: | Q6AI14 |
| Protein Name: | Sodium/hydrogen exchanger 4 |
| Length: | 798 |
| Molecular Weight: | 89814.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Apical cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), hydron |
Cross database links:
| Entrez Gene ID: | 389015 |
|---|---|
| Pfam: | PF00999 |
| KEGG: | hsa:389015 |
Gene Ontology
GO:0016324
C:apical plasma membrane
GO:0016323
C:basolateral plasma membrane
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015385
F:sodium:hydrogen antiporter activity
GO:0006811
P:ion transport
GO:0006885
P:regulation of pH
GO:0055085
P:transmembrane transport
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References (3)[1] “The full-ORF clone resource of the German cDNA consortium.” Bechtel S.et.al. 17974005 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MALQMFVTYS PWNCLLLLVA LECSEASSDL NESANSTAQY ASNAWFAAAS SEPEEGISVF 61: ELDYDYVQIP YEVTLWILLA SLAKIGFHLY HRLPGLMPES CLLILVGALV GGIIFGTDHK 121: SPPVMDSSIY FLYLLPPIVL EGGYFMPTRP FFENIGSILW WAVLGALINA LGIGLSLYLI 181: CQVKAFGLGD VNLLQNLLFG SLISAVDPVA VLAVFEEARV NEQLYMMIFG EALLNDGITV 241: VLYNMLIAFT KMHKFEDIET VDILAGCARF IVVGLGGVLF GIVFGFISAF ITRFTQNISA 301: IEPLIVFMFS YLSYLAAETL YLSGILAITA CAVTMKKYVE ENVSQTSYTT IKYFMKMLSS 361: VSETLIFIFM GVSTVGKNHE WNWAFICFTL AFCQIWRAIS VFALFYISNQ FRTFPFSIKD 421: QCIIFYSGVR GAGSFSLAFL LPLSLFPRKK MFVTATLVVI YFTVFIQGIT VGPLVRYLDV 481: KKTNKKESIN EELHIRLMDH LKAGIEDVCG HWSHYQVRDK FKKFDHRYLR KILIRKNLPK 541: SSIVSLYKKL EMKQAIEMVE TGILSSTAFS IPHQAQRIQG IKRLSPEDVE SIRDILTSNM 601: YQVRQRTLSY NKYNLKPQTS EKQAKEILIR RQNTLRESMR KGHSLPWGKP AGTKNIRYLS 661: YPYGNPQSAG RDTRAAGFSD DDSSDPGSPS ITFSACSRIG SLQKQEAQEI IPMKSLHRGR 721: KAFSFGYQRN TSQEEYLGGV RRVALRPKPL FHAVDEEGES GGESEGKASL VEVRSRWTAD 781: HGHGRDHHRS HSPLLQKK