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2.A.36.5.9
The sodium/hydrogen exchanger 2, NHX2, of 546 aas and 13 TMSs. It catalyzes the low affinity electroneutral exchange of protons for cations such as Na+ or K+ across membranes, and may also exchange Li+ and Cs+ with a lower affinity. It is involved in vacuolar ion compartmentalization necessary for cell volume regulation and cytoplasmic Na+ detoxification (Yokoi et al. 2002). Its ortholog has also been studied in Phyllostachys edulis (moso bamboo) where its overexpression reduces salt tolerance (Wu et al. 2021).  

Accession Number:Q56XP4
Protein Name:Sodium/hydrogen exchanger 2
Length:546
Molecular Weight:60523.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate lithium(1+), sodium(1+), potassium(1+), caesium ion, hydron

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FASTA formatted sequence
1:	MTMFASLTSK MLSVSTSDHA SVVSLNLFVA LLCACIVIGH LLEENRWMNE SITALLIGLG 
61:	TGVVILLISR GKNSHLLVFS EDLFFIYLLP PIIFNAGFQV KKKQFFRNFV TIMAFGAIGT 
121:	VVSCTIISLG AIQFFKKLDI GTFDLGDFLA IGAIFAATDS VCTLQVLNQD ETPLLYSLVF 
181:	GEGVVNDATS VVLFNAIQSF DLTHLNHEAA FQFLGNFFYL FLLSTGLGVA TGLISAYVIK 
241:	KLYFGRHSTD REVALMMLMA YLSYMLAELF ALSGILTVFF CGIVMSHYTW HNVTESSRIT 
301:	TKHAFATLSF LAETFIFLYV GMDALDIEKW RFVSDSPGTS VAVSSILMGL VMLGRAAFVF 
361:	PLSFLSNLAK KHQSEKISIK QQVVIWWAGL MRGAVSMALA YNKFTRSGHT ELRGNAIMIT 
421:	STITVCLFST MVFGMLTKPL IRYLMPHQKA TTSTTSMLSD DSTPKSIHIP LLDGEQLDSF 
481:	ELPGSHQDVP RPNSLRGFLM RPTRTVHYYW RQFDDAFMRP VFGGRGFVPF VPGSPTERSS 
541:	HDLSKP