2.A.36.6.8 Na+/H+ antiporter of 424 aas, NhaP, that extrudes sodium in exchange for external protons. Has weak (if any) Li+/H+ antiport activity (Kuroda et al. 2004).
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Accession Number: | G3XD29 |
Protein Name: | Na(+)/H(+) antiporter NhaP |
Length: | 424 |
Molecular Weight: | 45486.00 |
Species: | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [208964] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate |
sodium(1+), hydron |
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1: MLDLVAAFIA LTTLLTYVNY RFIRLPPTIG VMATALVFSL IVQGLSELGY PILEVEMQEI
61: IRRIDFSEVL MTWFLPALLF AGALHVDLSD LRSYKWPIGL LATAGVLIAT FVIGGLAYYT
121: FPLFGWQVDF IYCLLFGALI SPTDPIAVLG ILKSAGAPKP LATTIVGESL FNDGTAVVVF
181: AIILGILQLG EAPTVSATAI LFVQEAIGGV VFGAVLGYGV FVMMRGIDQY QVEVMLTLAL
241: VIGGAALAAR LHVSAPIAMV VAGLIIGNHG RHYAMSDETR RYVDKFWELI DEILNALLFA
301: LIGLELLLLP FSWLHVAAAF ALGGAVLVSR LLTVGPAILV LRRFRGANRQ VPAGTIRILV
361: WGGLRGGVSV ALALSLPLGP ERDLILSLTY IVVLVSILLQ GLSIGPLVRR IYAGQPLEKS
421: EGAH