2.A.53.3.3 12 TMS Na+:bicarbonate symporter, BicA (Price et al., 2004; Shelden et al., 2010) (low affinity but high efficiency).
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Accession Number: | Q14SY0 |
Protein Name: | BicA |
Length: | 566 |
Molecular Weight: | 59605.00 |
Species: | Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) [32049] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
sodium(1+), hydrogencarbonate |
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1: MQITNKIHFR NIRGDIFGGL TAAVIALPMA LAFGVASGAG AEAGLWGAVL VGFFAALFGG
61: TPTLISEPTG PMTVVMTAVI AHFTASAATP EEGLAIAFTV VMMAGVFQII FGSLKLGKYV
121: TMMPYTVISG FMSGIGIILV ILQLAPFLGQ ASPGGGVIGT LQNLPTLLSN IQPGETALAL
181: GTVAIIWFMP EKFKKVIPPQ LVALVLGTVI AFFVFPPEVS DLRRIGEIRA GFPELVRPSF
241: SPVEFQRMIL DAAVLGMLGC IDALLTSVVA DSLTRTEHNS NKELIGQGLG NLFSGLFGGI
301: AGAGATMGTV VNIQSGGRTA LSGLVRAFVL LVVILGAASL TATIPLAVLA GIAFKVGVDI
361: IDWSFLKRAH EISPKGALIM YGVILLTVLV DLIVAVGVGV FVANVLTIER MSNLQSEKVQ
421: TVSDADDNIR LTTTEKRWLD EGQGRVLLFQ LSGPMIFGVA KAIAREHNAM GDCDALVFDI
481: GEVPHMGVTA SLALENAIEE ALDKERQVYI VGAAGQTRRR LEKLKLFKRV PPDKCLMSRE
541: EALKNAVLGI YPHLADGVTA PSSEMG