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2.A.57.2.2 Nucleoside (nucleobase, drug) transporter of 463 aas, AT1 or P2. Transports adenosine and adenine as well as the drugs, eflornithine, melarsoprol, pentamidine, diminazene and cordycepin (Schmidt et al. 2018; Zhang et al. 2022); Kasozi et al. 2022).
Accession Number:	Q9Y0H9
Protein Name:	TbAT1 aka AT1R
Length:	463
Molecular Weight:	51028.00
Species:	Trypanosoma brucei [5691]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	nucleoside, nucleobase, adenine, adenosine

Pfam:	PF01733
Gene Ontology GO:0016020 C:membrane GO:0005337 F:nucleoside transmembrane transporter activity GO:0006810 P:transport
References (1) [1] “A nucleoside transporter from Trypanosoma brucei involved in drug resistance.” Maser P.et.al. 10398598

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MLGFDSANEF IVYVTFLFFG MSVVVVTNSI FSMPFFFIEY YKYAQGKPDA KPEDPKFWKH 
61:	MFTYYSIAAF VVELVLASLM LTPIGRRISV TVRLGVGLVI PIVLVFSVMM VTIVTTTETG 
121:	AKVTIMLIAI ANGVAMTLCD AGNAALIAPF PTKFYSSVVW GIAVCGVVTS FFSIVIKTSM 
181:	EGGYHNMLIQ SRIYFGLVMF MQVISCALLV LLRKNPYAQK YAAEFRYAAR KGIDDKGAGG 
241:	DEGNGAAKGP ADQDDDPHGG DDTDKGNVMT ATVDPDTMKD MDQVESITTS QQMLMARVWN 
301:	VFWRVWPMLF ACFMVFFTTF LVYPAVYFAI KADTGDGWYL TIAAALFNLG DFLSRLCLQF 
361:	KALHVSPRWV LIGTFARMLP IIPLVLCVRS IITGPWLPYI LVHAWGFTYG YYGGISQIYA 
421:	PRTGSLTTAG ERSLAANWTI ISLLGGIFVG AMFALAVNEG LPK

2.A.57.2.2
Nucleoside (nucleobase, drug) transporter of 463 aas, AT1 or P2. Transports adenosine and adenine as well as the drugs, eflornithine, melarsoprol, pentamidine, diminazene and cordycepin (Schmidt et al. 2018; Zhang et al. 2022); Kasozi et al. 2022).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.57.2.2Nucleoside (nucleobase, drug) transporter of 463 aas, AT1 or P2. Transports adenosine and adenine as well as the drugs, eflornithine, melarsoprol, pentamidine, diminazene and cordycepin (Schmidt et al. 2018; Zhang et al. 2022); Kasozi et al. 2022).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.57.2.2
Nucleoside (nucleobase, drug) transporter of 463 aas, AT1 or P2. Transports adenosine and adenine as well as the drugs, eflornithine, melarsoprol, pentamidine, diminazene and cordycepin (Schmidt et al. 2018; Zhang et al. 2022); Kasozi et al. 2022).