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2.A.66.1.11 The Enhanced Disease Susceptibility Protein (EDS5), also called the Salicylate Induction Deficient (Sid1) protein; a chloroplast isochorismate exporter that exports isochorismate from the plastid to the cytosol (Rekhter et al. 2019).
Accession Number:	Q945F0
Protein Name:	EDS5
Length:	543
Molecular Weight:	59528.00
Species:	Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:	9
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	salicylate

RefSeq:	NP_195614.2
Entrez Gene ID:	830058
Pfam:	PF01554
KEGG:	ath:AT4G39030
Gene Ontology GO:0016021 C:integral to membrane GO:0005739 C:mitochondrion GO:0009536 C:plastid GO:0015297 F:antiporter activity GO:0015238 F:drug transmembrane transporter activity GO:0006952 P:defense response GO:0006855 P:drug transmembrane transport GO:0031348 P:negative regulation of defense response GO:0009624 P:response to nematode GO:0009697 P:salicylic acid biosynthetic process
References (2) [1] “EDS5, an essential component of salicylic acid-dependent signaling for disease resistance in Arabidopsis, is a member of the MATE transporter family.” Nawrath C.et.al. 11826312 [2] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.” Mayer K.F.X.et.al. 10617198

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MLIKSQRLTL FSPLLSKTRR IPVNSHQTLV AESVITRRTL GAITATPSFH KNPVVIRRRI 
61:	KLERVTRNCV RIDREIDEEE EEEEKERGDL VKQSIWEQMK EIVKFTGPAM GMWICGPLMS 
121:	LIDTVVIGQG SSIELAALGP GTVLCDHMSY VFMFLSVATS NMVATSLAKQ DKKEAQHQIS 
181:	VLLFIGLVCG LMMLLLTRLF GPWAVTAFTR GKNIEIVPAA NKYIQIRGLA WPFILVGLVA 
241:	QSASLGMKNS WGPLKALAAA TIINGLGDTI LCLFLGQGIA GAAWATTASQ IVSAYMMMDS 
301:	LNKEGYNAYS FAIPSPQELW KISALAAPVF ISIFSKIAFY SFIIYCATSM GTHVLAAHQV 
361:	MAQTYRMCNV WGEPLSQTAQ SFMPEMLYGA NRNLPKARTL LKSLMIIGAT LGLVLGVIGT 
421:	AVPGLFPGVY THDKVIISEM HRLLIPFFMA LSALPMTVSL EGTLLAGRDL KFVSSVMSSS 
481:	FIIGCLTLMF VTRSGYGLLG CWFVLVGFQW GRFGLYLRRL LSPGGILNSD GPSPYTVEKI 
541:	KSI

2.A.66.1.11
The Enhanced Disease Susceptibility Protein (EDS5), also called the Salicylate Induction Deficient (Sid1) protein; a chloroplast isochorismate exporter that exports isochorismate from the plastid to the cytosol (Rekhter et al. 2019).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.66.1.11The Enhanced Disease Susceptibility Protein (EDS5), also called the Salicylate Induction Deficient (Sid1) protein; a chloroplast isochorismate exporter that exports isochorismate from the plastid to the cytosol (Rekhter et al. 2019).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.66.1.11
The Enhanced Disease Susceptibility Protein (EDS5), also called the Salicylate Induction Deficient (Sid1) protein; a chloroplast isochorismate exporter that exports isochorismate from the plastid to the cytosol (Rekhter et al. 2019).