2.A.66.1.33
MDR efflux pump for quinolones (moxifloxacin, ciprofloxacin and levofloxacin) of 456 aas, DinF (Tocci et al. 2013).
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| Accession Number: | I6L8P4 |
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| Protein Name: | MATE efflux family protein DinF |
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| Length: | 456 |
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| Molecular Weight: | 49784.00 |
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| Species: | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) [170187] |
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| Number of TMSs: | 12 |
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| Substrate |
levofloxacin, ciprofloxacin, moxifloxacin |
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1: MNKKRTVDLI HGPILPSLLS FTFPILLSNI FQQLYNTADV LIVGRFLGQE SLAAVGATTA
61: IFDLIVGFTL GVGNGMGIVI ARYYGARNFT KIKEAVAATW ILGALLSILV MLLGFLGLYP
121: LLQYLDTPAE ILPQSYQYIS MIVTCVGVSF AYNLFAGLLR SIGDSLAALG FLIFSALVNV
181: VLDLYFITQL HLGVQSAGLA TIISQGLSAV LCFYYIRKSV PELLPQFKHF KWDKSLYADL
241: LEQGLAMGLM SSIVSIGSVI LQFSVNTFGA VIISAQTAAR RIMTFALLPM TAISASMTTF
301: ASQNLGAKRP DRIVQGLRIG SRLSISWAVF VCIFLFFASP ALVSFLASST DGYLIENGSL
361: YLQISSTFYP ILSLLLIYRN CLQGLGQKIL PLVSSFIELI GKIVFVVLII PWAGYKGVIL
421: CEPLIWVAMT VQLYFSLFRH PLIKEGKAIL ATKVQS