2.A.66.1.49
MATE family transporter of 475 aas and 12 TMSs in a 6 + 6 TMS pseudosymmetic arrangement. The 3-d structure has been determined at 2.9 Å resolution (Tanaka et al. 2017). The protein possesses a negatively charged internal pocket with an outward-facing shape. This structure was determined for the C. sativa orthologue of the C. rubella protein, the sequence of which is 94% identical to the one provided here.
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| Accession Number: | R0G998 |
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| Protein Name: | Protein DETOXIFICATION |
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| Length: | 475 |
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| Molecular Weight: | 51676.00 |
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| Species: | Capsella rubella [81985] |
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| Number of TMSs: | 12 |
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| Substrate |
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1: MEEPFLQREE LVTTKATWPS GQLTAELKRV SRLAAPMATV TIAQYLLPVI SVMVAGHNGE
61: LQLSGVALAT SFTNVTGFSI MYGLVGALET LCGQAYGAKQ YEKIGTYAYS AIASNIPICF
121: LISILWIYIE KILISLGQDP DISRIAGSYA FWLIPVLYAQ AIVIPLTRFL LTQGLVLPLL
181: YTAVTTLLFH VLVCWALVFV FVLGGNGPAM ATSVSFWFYA MMLSCYVRFS SSCEKTRGFV
241: SEDFVSCVKQ FFQYGIPSAA MICLEWWLFE LLLLCSGLLP NPKLETSVLS ICLTTETLHY
301: VISSGVAAAV STRVSNSLGA GNPQVARVSV LAGLCLWLVE SAFFSILLFT CRNIVGYTFS
361: NSKEVVDYVA DLSPLLCLSF ILDGFTAVLN GVARGSGWQH IGAWNNIVSY YLVGAPVGIY
421: LAFSHDLKGK GLWCGVVVGS TVQATVLAIV TASMNWKEQA EKARKRIVST ENELA