TCDB » SEARCH

« See all members of the family

2.A.66.1.5 Ethionine resistance protein, ERC1, of 581 aas and 11 TMSs in a 6 + 5 TMS arrangement. It catalyzes S-adenosyl methionine (SAM) accumulation in Sake yeast (Kanai et al. 2017).
Accession Number:	P38767
Protein Name:	YHJ2 aka ERC1 aka YHR032w
Length:	581
Molecular Weight:	64209.00
Species:	Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	S-adenosyl-L-methionine, L-ethionine

DIP:	DIP-1785N
RefSeq:	NP_011897.1
Entrez Gene ID:	856427
Pfam:	PF01554
KEGG:	sce:YHR032W
Gene Ontology GO:0016021 C:integral to membrane GO:0015297 F:antiporter activity GO:0015238 F:drug transmembrane transporter activity GO:0006855 P:drug transmembrane transport
References (2) [1] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.” Johnston M.et.al. 8091229 [2] “A global topology map of the Saccharomyces cerevisiae membrane proteome.” Kim H.et.al. 16847258

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MSKQFSHTTN DRRSSIIYST SVGKAGLFTP ADYIPQESEE NLIEGEEQEG SEEEPSYTGN 
61:	DDETEREGEY HSLLDANNSR TLQQEAWQQG YDSHDRKRLL DEERDLLIDN KLLSQHGNGG 
121:	GDIESHGHGQ AIGPDEEERP AEIANTWESA IESGQKISTT FKRETQVITM NALPLIFTFI 
181:	LQNSLSLASI FSVSHLGTKE LGGVTLGSMT ANITGLAAIQ GLCTCLDTLC AQAYGAKNYH 
241:	LVGVLVQRCA VITILAFLPM MYVWFVWSEK ILALMIPERE LCALAANYLR VTAFGVPGFI 
301:	LFECGKRFLQ CQGIFHASTI VLFVCAPLNA LMNYLLVWND KIGIGYLGAP LSVVINYWLM 
361:	TLGLLIYAMT TKHKERPLKC WNGIIPKEQA FKNWRKMINL AIPGVVMVEA EFLGFEVLTI 
421:	FASHLGTDAL GAQSIVATIA SLAYQVPFSI SVSTSTRVAN FIGASLYDSC MITCRVSLLL 
481:	SFVCSSMNMF VICRYKEQIA SLFSTESAVV KMVVDTLPLL AFMQLFDAFN ASTAGCLRGQ 
541:	GRQKNRWVHQ PSRILLPRCA HGICVSIPVS SGCRRLMVGY N

2.A.66.1.5
Ethionine resistance protein, ERC1, of 581 aas and 11 TMSs in a 6 + 5 TMS arrangement. It catalyzes S-adenosyl methionine (SAM) accumulation in Sake yeast (Kanai et al. 2017).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.66.1.5Ethionine resistance protein, ERC1, of 581 aas and 11 TMSs in a 6 + 5 TMS arrangement. It catalyzes S-adenosyl methionine (SAM) accumulation in Sake yeast (Kanai et al. 2017).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.66.1.5
Ethionine resistance protein, ERC1, of 581 aas and 11 TMSs in a 6 + 5 TMS arrangement. It catalyzes S-adenosyl methionine (SAM) accumulation in Sake yeast (Kanai et al. 2017).