2.A.66.1.57
DETOXIFICATION 41, DTX41, TDS3, TT12 of 507 aas and 12 TMSs. Acts as a flavonoid/H+-antiporter that controls the vacuolar sequestration of flavonoids in the seed coat endothelium (Debeaujon et al. 2001; Marinova et al. 2007). May also transport the anthocyanin cyanidin-3-O-glucoside (Marinova et al. 2007) and epicatechin 3'-O-glucoside (Zhao and Dixon 2009).
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| Accession Number: | Q9LYT3 |
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| Protein Name: | Protein DETOXIFICATION 41 |
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| Length: | 507 |
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| Molecular Weight: | 55147.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Vacuole membrane1 / Multi-pass membrane protein2 |
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| Substrate |
flavonoid, anthocyanin cation |
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1: MSSTETYEPL LTRLHSDSQI TERSSPEIEE FLRRRGSTVT PRWWLKLAVW ESKLLWTLSG
61: ASIVVSVLNY MLSFVTVMFT GHLGSLQLAG ASIATVGIQG LAYGIMLGMA SAVQTVCGQA
121: YGARQYSSMG IICQRAMVLH LAAAVFLTFL YWYSGPILKT MGQSVAIAHE GQIFARGMIP
181: QIYAFALACP MQRFLQAQNI VNPLAYMSLG VFLLHTLLTW LVTNVLDFGL LGAALILSFS
241: WWLLVAVNGM YILMSPNCKE TWTGFSTRAF RGIWPYFKLT VASAVMLCLE IWYNQGLVII
301: SGLLSNPTIS LDAISICMYY LNWDMQFMLG LSAAISVRVS NELGAGNPRV AMLSVVVVNI
361: TTVLISSVLC VIVLVFRVGL SKAFTSDAEV IAAVSDLFPL LAVSIFLNGI QPILSGVAIG
421: SGWQAVVAYV NLVTYYVIGL PIGCVLGFKT SLGVAGIWWG MIAGVILQTL TLIVLTLKTN
481: WTSEVENAAQ RVKTSATENQ EMANAGV