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2.A.66.1.6 Drug (norfloxacin, ciprofoxacin, ethidium, tetramethylammonium, pyrrolidinone, polyvinylpyrrolidone) resistance pump, Alf5 or DTOXIFICATION 19, DTX19, of 427 aas and 12 TMSs. Note: A. thaliana has 56 MATE transporters (Takanashi et al. 2013).
Accession Number:	Q9LUH2
Protein Name:	Alf5 aka AT3G23550 aka MDB19.4
Length:	477
Molecular Weight:	51852.00
Species:	Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Golgi apparatus membrane¹ / Multi-pass membrane protein²
Substrate	tetramethylammonium, ciprofloxacin, norfloxacin, pyrrolidin-2-one, ethidium, poly(vinylpyrrolidone)

RefSeq:	NP_566730.1
Entrez Gene ID:	821935
Pfam:	PF01554
KEGG:	ath:AT3G23560
Gene Ontology GO:0016020 C:membrane GO:0015297 F:antiporter activity GO:0015238 F:drug transmembrane transporter activity GO:0006855 P:drug transmembrane transport
References (1) [1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.” Salanoubat M.et.al. 11130713

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MADPATSSPL LDDHVGGEDE RGRRSRSSTL VQKVIDVEEA KAQMIYSLPM ILTNVFYYCI 
61:	PITSVMFASH LGQLELAGAT LANSWATVSG FAFMVGLSGS LETLCGQGFG AKRYRMLGVH 
121:	LQSSCIVSLV FSILITIFWF FTESIFGLLR QDPSISKQAA LYMKYQAPGL LAYGFLQNIL 
181:	RFCQTQSIIA PLVIFSFVPL VINIATAYVL VYVAGLGFIG APIATSISLW IAFLSLGTYV 
241:	MCSEKFKETW TGFSLESFRY IVINLTLSLP SAAMVCLEYW AFEILVFLAG VMPNPEINTS 
301:	LVAICVNTEA ISYMLTYGLS AAASTRVSNE LGAGNVKGAK KATSVSVKLS LVLALGVVIV 
361:	LLVGHDGWVG LFSDSYVIKE EFASLRFFLA ASITLDSIQG VLSGVARGCG WQRLVTVINL 
421:	ATFYLIGMPI AAFCGFKLKF YAKGLWIGLI CGIFCQSSSL LLMTIFRKWT KLNVATV

2.A.66.1.6
Drug (norfloxacin, ciprofoxacin, ethidium, tetramethylammonium, pyrrolidinone, polyvinylpyrrolidone) resistance pump, Alf5 or DTOXIFICATION 19, DTX19, of 427 aas and 12 TMSs. Note: A. thaliana has 56 MATE transporters (Takanashi et al. 2013).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.66.1.6Drug (norfloxacin, ciprofoxacin, ethidium, tetramethylammonium, pyrrolidinone, polyvinylpyrrolidone) resistance pump, Alf5 or DTOXIFICATION 19, DTX19, of 427 aas and 12 TMSs. Note: A. thaliana has 56 MATE transporters (Takanashi et al. 2013).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.66.1.6
Drug (norfloxacin, ciprofoxacin, ethidium, tetramethylammonium, pyrrolidinone, polyvinylpyrrolidone) resistance pump, Alf5 or DTOXIFICATION 19, DTX19, of 427 aas and 12 TMSs. Note: A. thaliana has 56 MATE transporters (Takanashi et al. 2013).