3.E.1.1.20
A light-driven Li+/Na+-pumping rhodopsin with a DTG motifhas been characterized. It is of 250 aas and has 7 TMSs. The MpR E33Q mutant transported H+ in place of Li+/Na+, suggesting that Glu33 is a Li+/Na+ binding site on the cytoplasmic side. Gly93 in MpR was replaced by Asp to convert it from the Li+/Na+ pump to an H+ pump (Cho et al. 2021).
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| Accession Number: | QDI83736.1 |
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| Protein Name: | QDI83736.1 rhodopsin [Methylorubrum populi] |
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| Length: | 251 |
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| Molecular Weight: | |
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| Species: | Methylorubrum populi [223967] |
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| Number of TMSs: | 7 |
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| Substrate |
lithium(1+), sodium(1+), hydron |
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1: MTPQFWLWLG FAGMAAGAAA ILFIGKRRTH AEEADTIIHG IVPIIAACSY FAMATGQGSL
61: VLPAGPEAAD AARQFYFARY IDWTFTTPLL LLGLSRTAMH SGMRRPAVVW GLIGSDLLMI
121: VTALAFGLSV VAWVKWTWFA ISCGAFLAVF YGIFVQLREE NASERTDVRS AFLRNAIFLS
181: VVWCAYPVVL LIGQDGLGLL SPALALAVIA VLDLTAKVVY GIMATVQTTR AVDRDLAEGR
241: TAATPLRRAA