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3.E.1.1.4
Archaerhodopsin 3, archaerhodopsin-3, AR3, Aop3, BACR3 of 258 aas and 7 TMSs.  It pumps protons in response to light absorption (Saint Clair et al. 2012) and is 86% identical to 3.E.1.1.2. Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization (Bada Juarez et al. 2021). Opsin-based transmembrane voltage sensors (OTVSs) are membrane proteins increasingly used in optogenetic applications to measure voltage changes across cellular membranes (Mei et al. 2021).

Accession Number:P96787
Protein Name:Archaerhodopsin-3
Length:258
Molecular Weight:27746.00
Species:Halorubrum sodomense [35743]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate H+

Cross database links:

Structure:
6GUX   6GUY   6GUZ   6S63   6S6C     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDPIALQAGY DLLGDGRPET LWLGIGTLLM LIGTFYFLVR GWGVTDKDAR EYYAVTILVP 
61:	GIASAAYLSM FFGIGLTEVT VGGEMLDIYY ARYADWLFTT PLLLLDLALL AKVDRVTIGT 
121:	LVGVDALMIV TGLIGALSHT AIARYSWWLF STICMIVVLY FLATSLRSAA KERGPEVAST 
181:	FNTLTALVLV LWTAYPILWI IGTEGAGVVG LGIETLLFMV LDVTAKVGFG FILLRSRAIL 
241:	GDTEAPEPSA GADVSAAD