3.E.1.4.8 Yro2 of 344 aas and 7 TMSs. Plays a role in acetic acid tolereance and is induced by acetic acid stress and by entry into the stationary phase. It is 72% identical to Mrh1 (TC# 3.E.1.4.6) which is also believed to be involved in the acetic acid stress response (Takabatake et al. 2015).
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Accession Number: | P38079 |
Protein Name: | Protein YRO2 |
Length: | 344 |
Molecular Weight: | 38720.00 |
Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
acetic acid |
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1: MSDYVELLKR GGNEAIKINP PTGADFHITS RGSDWLFTVF CVNLLFGVIL VPLMFRKPVK
61: DRFVYYTAIA PNLFMSIAYF TMASNLGWIP VRAKYNHVQT STQKEHPGYR QIFYARYVGW
121: FLAFPWPIIQ MSLLGGTPLW QIAFNVGMTE IFTVCWLIAA CVHSTYKWGY YTIGIGAAIV
181: VCISLMTTTF NLVKARGKDV SNVFITFMSV IMFLWLIAYP TCFGITDGGN VLQPDSATIF
241: YGIIDLLILS ILPVLFMPLA NYLGIERLGL IFDEEPAEHV GPVAEKKMPS PASFKSSDSD
301: SSIKEKLKLK KKHKKDKKKA KKAKKAKKAK KAQEEEEDVA TDSE