3.E.1.7.4
Channelopsin, MChR1 (Govorunova et al., 2011). In another channelrhodopsin (CrChR2) of this family, an E97A mutation in TMS 2 prevents high affiinity binding of the inhibitor, Gd3+ and interfers with photocurrent, but this ChR1 with an alanine at this position, has low affininty for Gd3+ but normal photocurrent (Watanabe et al. 2016).
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| Accession Number: | F8UVI5 |
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| Protein Name: | Channelopsin 1 |
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| Length: | 593 |
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| Molecular Weight: | 65743.00 |
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| Species: | Mesostigma viride [41882] |
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| Number of TMSs: | 8 |
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| Substrate |
hydron |
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| Pfam: |
PF01036
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[1] “New Channelrhodopsin with a Red-Shifted Spectrum and Rapid Kinetics from Mesostigma viride.” Govorunova E.G. et.al. 21693637
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1: MSPPTSPTPD TGHDTPDTGH DTGGHGAVEI CFAPCEEDCV TIRYFVENDF EGCIPGHFDQ
61: YSSHGSLHDI VKAALYICMV ISILQILFYG FQWWRKTCGW EVWFVACIET SIYIIAITSE
121: ADSPFTLYLT NGQISPQLRY MEWLMTCPVI LIALSNITGM AEEYNKRTMT LLTSDVCCIV
181: LGMMSAASKP RLKGILYAVG WAFGAWTYWT ALQVYRDAHK AVPKPLAWYV RAMGYVFFTS
241: WLTFPGWFLL GPEGLEVVTG TVSTLMHACS DLISKNLWGF MDWHLRVLVA RHHRKLFKAE
301: EEHALKKGQT LEPGMPRSTS FVRGLGDDVE IDPSYELYRL KRQNHPEYFL SPAQTPRRGP
361: SFDKRTSFEM DGGKNGMLQM MPVTGMGMGM GMGMGGGKTV LFLDYTGGGY VSFFEQQLSN
421: MGVNVTKCWS DDDMYNTAGV ANVKQLFHFA MIPNNALGGQ MVMDLRGTGL LVVAYGPEPP
481: MPGMGQDEFV PLQMPGVPYD ESILHNLVMR HAITQGLGMN GMQGNMGQQQ QMMGMQGNMN
541: GMQGNMNGMQ GNMNGMQGNM SGMQGNMNGM QGNSGMNQGW NNQGFTNTGA FGY