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4.C.3.1.1 Peroxisomal Acyl-CoA thioesterase 5, Acot5 (2-4 putative TMSs) It has two domains: N-terminal bile acid-CoA:amino acid N-acetyl transferase domain and a C-terminal Acyl-CoA thioester hydrolase domain.
Accession Number:	Q6Q2Z6
Protein Name:	Acot5
Length:	421
Molecular Weight:	46520.00
Species:	Mus musculus (Mouse) [10090]
Number of TMSs:	3
Location¹ / Topology² / Orientation³:	Peroxisome¹
Substrate	acyl-CoA

Pfam:	PF04775
Gene Ontology GO:0005829 C:cytosol GO:0005777 C:peroxisome GO:0004091 F:carboxylesterase activity GO:0016290 F:palmitoyl-CoA hydrolase activity GO:0006637 P:acyl-CoA metabolic process GO:0001676 P:long-chain fatty acid metabolic process GO:0032788 P:saturated monocarboxylic acid metabolic pro... GO:0032789 P:unsaturated monocarboxylic acid metabolic p... GO:0000038 P:very-long-chain fatty acid metabolic process
References (2) [1] “Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.” Westin M.A.K.et.al. 15007068 [2] “Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.” Lee J.et.al. 17208939

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MVPTVSLEPT GHSCWDEPLS IAVRGLAPEQ PVTLRTALRD EKGALFRAHA RYRADSHGEL 
61:	DLARTPALGG SFSGLEPMGL LWAMEPDRPF WRLIKRDVQT PFVVELEVLD GHEPDGGRLL 
121:	ARAVHECHFM APGVRRVPVR EGRVRATLFL PPGTGPFPGI IDLFGVGGGL LEYRASLLAG 
181:	KGFAVMALAY YKYDDLPKVI DILHLEYFEE AVTYLLSHPQ VKGPGVGLLG ISKGAELSLS 
241:	MASFLKGITA AVVINGATVN VISTLYYKEE SLPGLGMHLE RIKVTKDGFK DIIDILNVPL 
301:	EAPDQKSLIP LERSDTAFLF LVGQDDHNWK SEFYAREASK RLQAHGKEKP QIVCYPKTGH 
361:	HIEPPYIPWS IAAPHSYFDK PILLGGEPRA HAMAQVDAWQ RLQTFFHKHL SGDKRPSPAK 
421:	L

4.C.3.1.1
Peroxisomal Acyl-CoA thioesterase 5, Acot5 (2-4 putative TMSs) It has two domains: N-terminal bile acid-CoA:amino acid N-acetyl transferase domain and a C-terminal Acyl-CoA thioester hydrolase domain.

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

4.C.3.1.1Peroxisomal Acyl-CoA thioesterase 5, Acot5 (2-4 putative TMSs) It has two domains: N-terminal bile acid-CoA:amino acid N-acetyl transferase domain and a C-terminal Acyl-CoA thioester hydrolase domain.

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

4.C.3.1.1
Peroxisomal Acyl-CoA thioesterase 5, Acot5 (2-4 putative TMSs) It has two domains: N-terminal bile acid-CoA:amino acid N-acetyl transferase domain and a C-terminal Acyl-CoA thioester hydrolase domain.