4.H.1.1.2
Putative oxacillin resistance-associated protein, FmtC (872 aas; 14 N-terminal TMSs (residues 1-530) plus a largely hydrophilic DUF2156 domain (residues 531-872). Similar throughout its length to FmtC of Staphylococcus aureus (2.A.1.3.35). Residues 67-326 (TMSs 2-8) are homologous to residues 527-786 (TMSs 8-14) in Rv0585c of Mycobacterium tuberculosis (2.A.1.3.43). Residues 6-314 are also homologous to an extra hydrophobic domain in Mg2+ P-type ATPases (3.A.3.4.3 and 3.A.3.4.4). The C-terminal domain belongs to the DUF2156 superfamily. Homologues of the hydrophilic domain retrieved with NCBI BLAST searches are annotated as "putative" lysylphosphatidyl-glycerol synthetase. Some include full length MFS fusion proteins.
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| Accession Number: | D1F3T8 |
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| Protein Name: | Putative uncharacterized protein |
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| Length: | 872 |
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| Molecular Weight: | 95369.00 |
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| Species: | Brucella melitensis bv. 3 str. Ether [520466] |
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| Number of TMSs: | 15 |
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| Substrate |
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1: MSLIDDEIPS SQPQVSGRHF GWLKQYQHFL FPIAGIAIAL LAIYVLENLL RHTSRTETLA
61: ALHNISWTTL ALAVFFTALS YAAVALYDVV AVDTIAPNQI PRRIAAVAGA AGYAISNALG
121: FSLLTGGALR YRIYAAEGIS LADIGKIVGT SWFAIWFALI IMVGAALLID PQDVPFLSAI
181: DIRIDIVAGI LILGGIGWLI YWLSHGERNV SIGSFSLRLP NSKGALTQIF AGVVDVGAAA
241: ATLYVLLPEG AVPSFAIFAL VYVIAIVLGI ASHAPGGLGA FEATIIAGLG LGGKPDAIAG
301: LLAYRLIYTV LPLVVATAGI LIWEVMRRRH MLDKQARFAK RLVEPLVPGL SASIIFLGGI
361: ILLISGATPD MRYRVKLLSD IVPEFLVEMS HLAASLVGVA LLIVARGLSK RLERAWVAAM
421: VLLLCGAVFS IAKGLDWEEA SILCLFALSL WGFRDSFYRR PIAGPFELSW NWIATVGTTV
481: LVSTWLGFFV YRHIEYSSDL WWDFAWNGNA PRFLRATVLV FAVVAAVGLH SIINRHGQRR
541: RKVDHSIPDA VPALVARCPH TDAALAMLGD KQFLLAPDDS AFIMYAQSGG SLIALGEPIG
601: DAEAGKELAW SFHSLADRLA LRTVFYGVGP QSLPLFLDMG LIALKLGEVA RVDLTDFSLE
661: GPRRQPFRYA DRKVDKDGLT FEIIPAADVP PLIPRLRAIS DAWLDHKSGS EKGFSLGYFN
721: DEYLKRFDIA VLKKDGEIVA FANIWRGADK YEITVDLMRY MPNVHKLLMD GLFAKLLTFS
781: KQEGYKWFNL GAAPLSGLSG SRLASRWNRF GSFIYRRGAD LYHFDGLKVF KEKFDPVWTP
841: HYMVCPGGLK TPRALLDATT LINGSPLEFI RK