4.H.1.1.5
Bifunctional alanyl phosphatidylglycerol flippase/synthetase MprF of 878 aas and 15 TMSs in a 14 + 1 TMS arrangement.The structure of the synthase domain has been determined (Hebecker et al. 2015). There may be a C-terminal TMS in addition to the 15 TMSs cited above.
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| Accession Number: | WP_106451403.1 |
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| Protein Name: | WP_106451403.1 bifunctional lysylphosphatidylglycerol flippase/synthetase MprF [Pseudomonas aeruginosa] |
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| Length: | 879 |
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| Molecular Weight: | |
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| Species: | Pseudomonas aeruginosa [287] |
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| Number of TMSs: | 15 |
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| Substrate |
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1: MRWLMRTDAP PSSPASPQRI RLIDRITAYR QPIGLVFTLL LFGLALVACY HLLREIDPGA
61: LHDAIADVPR PALLGALGAT ALGFVILLGY EWSASRFAGV TLPMRSLATG GFSAFAIGNA
121: VGLSLLSGGS VRYRLYSRHG IGAAEIARMT LFASLSLGCA LPVLAALAAL CDLDDAASAL
181: HLPRALVAVI AIAVLSLAVG LVAFLARHRL PGERPSPDSL LVRLGRRSLR LPGLRLSLLQ
241: LLITALDVAA AATVLYLLLP ETPPFAAFLL VYLLALAAGV LSHVPGGVGV FEAVLLAAFA
301: GQLGAAPLAA ALLLYRLIYV VLPLLLACLL LLFLEARRLW VTRQAIRVAS GFAAPILAIL
361: VFLSGVVLLF SGATPAIDTR LEHLGFLIPH RLIDASHLVA SLIGVLCLLL AQGLRRRLSA
421: AWALTLVLLL VGALLSLLKG FDWEEASLLS LTAALLAMFR RSFYRPSRLM EVPFSPLYVG
481: ASICVVGASV WLLLFANQDV HYSNQLWWQF ALDADAPRAL RAALGSCLLL LALALGWLLR
541: AAPPAIREPN AEELQRAARI IRHSDQPDGG LALTGDKALL FHESDDAFLM YARRGRSMIA
601: LYDPIGPAMQ RAELIWQFRD LCDLHHARPV FYQVRAENLP FYMDIGLTAL KLGEEARVDL
661: LRFDLENKGK EMKDLRYTWN RGQRDGLALE FHEPGQAPLD ELKAISDAWL GGKQVREKGF
721: SLGRFTPAYL NFFRIAIVRH QGKPVAFANL LETDSRELAS LDLMRVHPDA PKLTMEFLML
781: GLILHYKAQG HARFSLGMVP LAGLQPRRGA PLTQRLGALV FRRGEQFYNF QGLRRFKDKF
841: QPDWEPRYLA VPAGLDPLVA LADTAALIAG GLTGLVKR