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8.A.107.  The V-type ATPase assembly factor, ATP6AP1 (ATP6AP1) Family 

Atp6ap1b functions to localize the V-ATPase to the plasma membrane where it regulates proton flux and cytoplasmic pH in humans and zebrafish (Gokey et al. 2015). It forms a complex with ATP6AP2 which serves the same function (Guida et al. 2018). It has been given the designation of the Vacuolar ATP synthase subunit S1 (ATP6S1) family in the conserved domain database, CDD.

References associated with 8.A.107 family:

Gokey, J.J., A. Dasgupta, and J.D. Amack. (2015). The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left-right asymmetry in zebrafish. Dev Biol 407: 115-130. 26254189
Guida, M.C., T. Hermle, L.A. Graham, V. Hauser, M. Ryan, T.H. Stevens, and M. Simons. (2018). ATP6AP2 functions as a V-ATPase assembly factor in the endoplasmic reticulum. Mol. Biol. Cell mbcE18040234. [Epub: Ahead of Print] 29995586
Rujano, M.A., M. Cannata Serio, G. Panasyuk, R. Péanne, J. Reunert, D. Rymen, V. Hauser, J.H. Park, P. Freisinger, E. Souche, M.C. Guida, E.M. Maier, Y. Wada, S. Jäger, N.J. Krogan, O. Kretz, S. Nobre, P. Garcia, D. Quelhas, T.D. Bird, W.H. Raskind, M. Schwake, S. Duvet, F. Foulquier, G. Matthijs, T. Marquardt, and M. Simons. (2017). Mutations in the X-linked cause a glycosylation disorder with autophagic defects. J Exp Med 214: 3707-3729. 29127204
Schoonderwoert, V.T. and G.J. Martens. (2002). Structural gene organization and evolutionary aspects of the V-ATPase accessory subunit Ac45. Biochim. Biophys. Acta. 1574: 245-254. 11997089