8.A.108.1.9
Receptor Expression-Enhancing Protein 6, REEP6, of 211 aas and probably 4 TMSs in a 2 + 2 TMS arrangement. The clinical and biological effects of REEP6 on tongue squamous cell carcinoma (TSCC) have been studied (Tseng et al. 2023). REEP6 controls the expression or transport of a subset of proteins/receptors. Thus, REEP6 is involved in the malignancy of TSCC and might serve as a potential diagnostic/prognostic biomarker and therapeutic target for TSCC patients (Tseng et al. 2023).
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| Accession Number: | Q96HR9 |
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| Protein Name: | Receptor expression-enhancing protein 6 |
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| Length: | 211 |
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| Molecular Weight: | 23418.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MDGLRQRVEH FLEQRNLVTE VLGALEAKTG VEKRYLAAGA VTLLSLYLLF GYGASLLCNL
61: IGFVYPAYAS IKAIESPSKD DDTVWLTYWV VYALFGLAEF FSDLLLSWFP FYYVGKCAFL
121: LFCMAPRPWN GALMLYQRVV RPLFLRHHGA VDRIMNDLSG RALDAAAGIT RNVLQVLARS
181: RAGITPVAVA GPSTPLEADL KPSQTPQPKD K