| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.116.1.1 | The transmembrane inner ear expressed protein, Tmie (153aas; 2 TMSs). Hair cells express two molecularly and functionally distinct mechanotransduction channels with different subcellular distributions. One is activated by sound and is responsible for sensory transduction. This sensory transduction channel is expressed in hair cell stereocilia, and its activity is affected by mutations in the genes encoding the transmembrane proteins TMHS (TC# 1.A.82.1.1), TMIE (this family), TMC1 and TMC2 (family 1.A.17.4) (Wu et al. 2017). The other is the Piezo2 channel (TC# 1.A.75.1.2) (Qiu and Müller 2018). | Eukaryota |
Metazoa, Chordata | Tmie of Mus musculus (Q8K467) |
|
8.A.116.1.2 | The transmembrane inner ear expressed protein, TMIE (156aas; 2 TMSs) (Fettiplace 2016). | Eukaryota |
Metazoa, Chordata | TMIE of Homo sapiens (Q8NEW7) |
|
8.A.116.2.1 | Uncharacterized protein | Eukaryota |
Metazoa, Nematoda | Uncharacterized protein of Caenorhabditis elegans |
|
8.A.116.3.1 | Uncharacterized protein of 117 aas and one TMS, CG15130, isoform B | Eukaryota |
Metazoa, Arthropoda | CG15130 isoform B of Drosophila melanogaster |