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8.A.117.1.5
Neuroligin-1 (NGLN1) of 798 aas and 2 TMSs. Iit is involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins, and it plays a role in the clustering of the GABA(A) receptor Unc-49 at postsynaptic sites in neuromuscular junctions via interactions with madd-4 and neurexin, nrx-1. It is is thereby required for normal GABAergic synaptic transmission (Maro et al. 2015, Tu et al. 2015).

Accession Number:Q9XTG1
Protein Name:Neuroligin-1
Length:798
Molecular Weight:89018.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Single-pass type I membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MERIYLLLLL FLPRIRSYDV RSVTTSWGMV RGEVVSPEGD DLPPVAQYLG IPYGVAPTGQ 
61:	YRFNMAISAA KWTHMPKDAR KVSPVCIQTD MPELSETKAF KHTSAQRFDF NHRLLPHLKK 
121:	QSEDCLYMNI YVPERLEISR DNYLPVMVIV HGEEYGWGTG NAFNGTTLAA YGHIIVVTLN 
181:	YRLGVFGFLG RCESSSCSGN SGISDLVSAL TMLNVILPSF GGDSKSVTLA GWGSGASLVS 
241:	LLMASPLTQP GRRLFRRAIL LDGSALSPWA ISQNPQQYFM QLAEELACAP KNRTSSFNDN 
301:	VDTIVRCMQV HSSENITKAV LKIDVPTFLS GFAPIVDGQL IPNKPQVSFS TQYGSLFREI 
361:	DLLVGISSNP SHHMISNEDL KVGISKEKRM RIFRSLVRNL YDFHREEILA SIINEYTDWE 
421:	NPRDHPKSIR NGVLNALSDV LYTAPLIETL RSHSADEVRK EANTFMFAFA HETRSWSQEQ 
481:	PNSGIRGSLS GDIVPYIFGY PLAQGDSEER LYSGFNTDDK GISKVMMHYV SNFVKSGDPS 
541:	KPNPMSKNFP MGDVFHSTAW PQFDQPNREA YLEITDRPRV KNYYRNAQVG FWNNFIPQLH 
601:	KNGKETEPVG EEHHLLSDHF RKDSYFGKTR HFSSYANLPF PPPPMPPSPP PELTTKPKPS 
661:	ESPTTLQTTT ESEKAAAGSF TGKALGGVIF IGCGFLIMNV CLLIAVRREW GKKRRNEKKF 
721:	QLQYQTYNSN HGGGAEQYNS LNSPEPLLSA SHKNSTSMRP AGISPTCPRH GRAALALQNS 
781:	RGNSLTAAQA PTLEEIQV