8.A.147.1.1 Tpx1 is a peroxiredoxin that binds hemin and regulates the
heme-iron/siderophore-iron transporter 3, Str3 (TC# 2.A.1.16.9). Tpx1
(Q74887; 192 aas and 0 - 2 possible TMSs), is a high affinity binding
partner of Str3 (Normant et al. 2020).
|
Accession Number: | O74887 |
Protein Name: | Peroxiredoxin tpx1 |
Length: | 192 |
Molecular Weight: | 21191.00 |
Species: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
Substrate |
hemin |
---|
1: MSLQIGKPAP DFKGTAVVNG AFEEIKLADY KGKWVFLGFY PLDFTFVCPT EIVAFSEAAS
61: KFAERNAQVI LTSTDSEYSH LAFINTPRKE GGLGGINIPL LADPSHKVSR DYGVLIEDAG
121: VAFRGLFLID PKGVLRQITI NDLPVGRSVD EALRLLDAFQ FVEEHGEVCP ANWHKGSDTI
181: DTKNPEKYFS KH