TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.168.1.1









Glycophorin A (GYPA or GPA) of 150 aas and 2 TMSs, one N-terminal and one near the C-terminus of the protein. Red blood cell sialoglycoproteins (glycophorins) play an important role in invasion by Plasmodium falciparum (Pasvol et al. 1992), but they also regulate the activities of several transport systems (see GP family description and Takakuwa 2001). GpA dimerization has been measured using molecular dynamics-based approaches that agree with experiments, and this allows the  protein-protein binding affinities in membranes (Blazhynska et al. 2023).

Eukaryota
Metazoa, Chordata
GPA of Homo sapiens
8.A.168.1.2









Glycophorin-A, GPA, isoform X1 of 230 aas and 2 TMSs, N- and C-terminal.

Eukaryota
Metazoa, Chordata
GPA of Sarcophilus harrisii
8.A.168.1.3









Glycophorin A, GPA, of 171 aas and 1 C-terminal TMS.  It may be N-terminally truncated. 

Eukaryota
Metazoa, Chordata
GPA of Meriones unguiculatus (Mongolian gerbil)
8.A.168.1.4









Glycophorin B, GPB, of 82 aas and 1 C-terminal TMS. (may be N-terminally truncated).

Eukaryota
Metazoa, Chordata
GPB of Homo sapiens