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|---|---|
| Accession Number: | Q9JK00 |
| Protein Name: | SCN3B aka SCNB3 |
| Length: | 215 |
| Molecular Weight: | 24799.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 2 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Single-pass type I membrane protein2 |
| Substrate | |
Cross database links:
| RefSeq: | NP_620797.1 |
|---|---|
| Entrez Gene ID: | 245956 |
| Pfam: | PF07686 |
| KEGG: | rno:245956 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005272
F:sodium channel activity
GO:0005244
F:voltage-gated ion channel activity
GO:0019233
P:sensory perception of pain
GO:0006814
P:sodium ion transport
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References (5)[1] “Beta3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics.” Morgan K.et.al. 10688874 [2] “Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunits.” Qu Y.et.al. 11922146 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain.” Ratcliffe C.F.et.al. 11470829 [5] “Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channel.” Vijayaragavan K.et.al. 15178439
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MPAFNRLLPL ASLVLIYWVR VCFPVCVEVP SETEAVQGNP MKLRCISCMK REEVEATTVV 61: EWFYRPEGGK DFLIYEYRNG HQEVESPFQG RLQWNGSKDL QDVSITVLNV TLNDSGLYTC 121: NVSREFEFEA HRPFVKTTRL IPLRVTEEAG EDFTSVVSEI MMYILLVFLT LWLFIEMIYC 181: YRKVSKAEEA AQENASDYLA IPSENKENSV VPVEE