TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.171.1.1









Transmembrane protein 168, TMEM168, of 697 aas and 13 or 14 TMS in a 4 + 5 or 6 + 3 TMS arrangement. TMEM168 mutations reduce cardiomyocyte cell surface expression of Nav1.5 (TC# 1.A.1.10.3) through alphaB-crystallin intracellular dynamics (see family description).

Eukaryota
Opisthokonta
TMEM168 of Homo sapiens
8.A.171.1.2









Uncharacterized TMEM168 homologue of 533 aas and 12 or 13 TMSs in a 4 + 3 + 2 + 2 or 3 + 1 TMS arrangement.

Eukaryota
Opisthokonta
TMEM168 of Paragonimus westermani
8.A.171.1.3









Uncharacterized protein of 503 aas and 12 TMSs in a 3 + 5 + 2 + 2 TMS arrangement.

Eukaryota
Opisthokonta
UP of Trichuris trichiura (human whipworm)
8.A.171.1.4









Uncharacterized TMEM168 homologue of 1163 aas and ~15 TMSs in a 2 + 2 + 3 + 3 + 3 +2 TMS arrangement.

Eukaryota
Opisthokonta
UP of Brachionus calyciflorus