TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.174.1.1









Cytochrome c oxidase assembly protein, COX15, of 410 aas and 7 or 8 TMSs in a 1 + 3 + 1 + 3 TMS arrangement.  A variant in the COX15 gene causes a fatal infantile cardioencephalomyopathy (Galvão de Oliveira et al. 2021). This protein is homologous but distantly related to a protein annotated as heme A synthase, CtaA (TC# 3.A.4.4.1; P12946).

Eukaryota
Metazoa, Chordata
Cox15 of Homo sapiens
8.A.174.1.2









COX15/CtaA family protein of 334 aas and 8 TMSs in a 1 + 3 + 1 + 3 TMS arrangement.

Bacteria
Pseudomonadota
Cox15 protein of Legionella sainthelensi
8.A.174.1.3









COX15/CtaA family protein of 338 aas and 8 TMSs in a 1 + 3 + 1 + 3 TMS arrangement, suggesting the presence of two repeat units.

Bacteria
Pseudomonadota
COX15 family protein of Methylotenera versatilis
8.A.174.1.4









Uncharacterized protein of 325 aas and 8 TMSs in a 1 + 3 + 1 + 3 TMS arrangement.

Bacteria
Pseudomonadota
UP of Blastochloris viridis
8.A.174.1.5









Uncharacterized protein of 448 aas and 12 TMSs in a 3 + 1 + 1 + 2 + 5 TMS arrangement.

Bacteria
Planctomycetota
8.A.174.1.6









COX15/CtaA family protein of 352 aas and 8 TMSs in a 1 + 3 + 1 + 3 TMS arrangement.

Bacteria
Chloroflexota
CtaA of Chloroflexi bacterium