8.A.196.1.2
Tapasin-related protein, TAPBPL, of 468 aas and 2 TMSs, N- and C-terminal. It is a component of the antigen processing and
presentation pathway, which binds to MHC class I coupled with
beta2-microglobulin/B2M. Association between TAPBPR and MHC class I
occurs in the absence of a functional peptide-loading complex (PLC).
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| Accession Number: | Q9BX59 |
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| Protein Name: | Tapasin-related protein |
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| Length: | 468 |
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| Molecular Weight: | 50183.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
peptide |
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1: MGTQEGWCLL LCLALSGAAE TKPHPAEGQW RAVDVVLDCF LAKDGAHRGA LASSEDRARA
61: SLVLKQVPVL DDGSLEDFTD FQGGTLAQDD PPIIFEASVD LVQIPQAEAL LHADCSGKEV
121: TCEISRYFLQ MTETTVKTAA WFMANMQVSG GGPSISLVMK TPRVTKNEAL WHPTLNLPLS
181: PQGTVRTAVE FQVMTQTQSL SFLLGSSASL DCGFSMAPGL DLISVEWRLQ HKGRGQLVYS
241: WTAGQGQAVR KGATLEPAQL GMARDASLTL PGLTIQDEGT YICQITTSLY RAQQIIQLNI
301: QASPKVRLSL ANEALLPTLI CDIAGYYPLD VVVTWTREEL GGSPAQVSGA SFSSLRQSVA
361: GTYSISSSLT AEPGSAGATY TCQVTHISLE EPLGASTQVV PPERRTALGV IFASSLFLLA
421: LMFLGLQRRQ APTGLGLLQA ERWETTSCAD TQSSHLHEDR TARVSQPS