| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.22.1.1 | Voltage-dependent Ca2+ channel (VSCC) β1-subunit, CACNB1 of 597 aas. VSCCs are composed of different subunits, α1, β, α2δ and γ, among which the cytosolic β subunit (Cavβ) controls the trafficking of the channel to the plasma membrane, its regulation and its gating properties. Many proteins interact with Cavβ, suggesting a multifunctional role of these proteins. Some of the newly assigned functions of Cavβ are independent of its role in the regulation of VGCC (Rima et al. 2016). | Eukaryota |
Metazoa | CACNB1 of Mus musculus (33146398) |
|
8.A.22.1.2 | Voltage-gated Ca2+ channel β2-subunit, CACNB2 | Eukaryota |
Metazoa | CACNB2 of Homo sapiens (18481641) |
|
8.A.22.1.3 | Dihydropyridine-sensitive L-type, Ca2+ channel β3-subunit, CACNB3. Oligomerization of Cavβ subunits is required for Ca2+ channel activity (Lao et al., 2010). | Eukaryota |
Metazoa | CACNB3 of Homo sapiens (1705683) |
|
8.A.22.1.4 | Ca2+ channel, voltage-dependent, β4-subunit, CACNB4 | Eukaryota |
Metazoa | CACNB4 of Homo sapiens (4502537) |