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8.A.68.1.2
TMN7 of the ER of 641 aas and 10 TMSs with 1 N-terminal followed at resudue 281 with 1 + 2 + 2 + 2 more TMSs at the C-terminus of the protein (Hegelund et al. 2010).  TM9 homologues from S. cerevisiae and A. thaliana affect the intracellular Copper ion (Cu) balance. Tmn1p and Tmn2p operate from the yeast vacuolar membrane without influencing vacuolar biogenesis. A new physiological function of the TM9 family coupled to vacuolar Cu homeostasis was proposed (Hegelund et al. 2010). A Golgi-located Transmembrane Nine Protein, TMN11, functions in Manganese/Cadmium homeostasis and regulates growth and seed development in rice (Li et al. 2022).

Accession Number:Q9LIC2
Protein Name:Multispanning membrane protein-like
Length:641
Molecular Weight:74234.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:10
Substrate

Cross database links:

Entrez Gene ID: 820587   
Pfam: PF02990   
KEGG: ath:AT3G13772    ath:AT3G13772   

Gene Ontology

GO:0005794 C:Golgi apparatus
GO:0016021 C:integral to membrane
GO:0005634 C:nucleus
GO:0005774 C:vacuolar membrane
GO:0006878 P:cellular copper ion homeostasis
GO:0006882 P:cellular zinc ion homeostasis

References (4)

[1] “Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the regions of 4,251,695 bp covered by ninety P1, TAC and BAC clones.”  Nakamura Y.et.al.   10907853
[2] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[3] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[4] “Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones.”  Nakamura Y.et.al.   10907853

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKKTKGSSFR FYATLLLSFL SFSLSRAFYL PGVAPRDFQK GDPLYVKVNK LSSTKTQLPY 
61:	DYYYLNYCKP PKILNNAENL GEVLRGDRIE NSVYTFQMLE DQPCKVGCRV KLNADSTKNF 
121:	KEKIDDEYRA NMILDNLPVA VLRQRRDGSQ STTYEHGFRV GFKGSYEGSK EEKYFIHNHL 
181:	SFRVMYHRDQ ESDSARIVGF EVTPNSILHE YKEWDEKNPQ LTTCNKDTKN LIQGNTVPQE 
241:	VEQGKEIVFT YDVSFKESEI KWASRWDTYL LMNDDQIHWF SIINSLMIVL FLSGMVAMIM 
301:	MRTLYKDISN YNQLETQDEA QEETGWKLVH GDVFRPPVNS GLLCVYVGTG VQIFGMSLVT 
361:	MMFALLGFLS PSNRGGLMTA MVLLWVFMGI FAGYSSSRLH KMFKGNKWKR MTLKTAFMFP 
421:	GILFAIFFVL NALIWGEQSS GAIPFGTMFA LFCLWFGISV PLVFVGSYLG YKKPAIEDPV 
481:	KTNKIPRQVP EQPWYMKPVF SILIGGILPF GAVFIELFFI LTSIWLNQFY YIFGFLFIVF 
541:	LILIVTCAEI TVVLCYFQLC SEDYNWWWRA YLTAGSSAFY LFLYSIFYFF TKLEITKLVS 
601:	GMLYFGYMII ISYAFFVLTG TIGFYACFWF VRKIYSSVKI D