8.B.19.2.1
U1-ctenitoxin Cs1a (CstX-7). Blocks mammalian neuronal L-type (Cav1/CACNA1) high-voltage-activated calcium channels.
Causes paralysis in Drosophila. Its insecticidal activity is
synergistically increased by potassium ions, M-ctenitoxin-Cs1a (P83619), omega-ctenitoxin-Cs1a (P81694), and U1-ctenitoxin-Cs2a (P83919). Because of the disulfide knot strcuture, this neurotoxin is called a knottin (Schalle et al. 2001).
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| Accession Number: | P58604 |
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| Protein Name: | U1-ctenitoxin-Cs1a |
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| Length: | 68 |
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| Molecular Weight: | 7539.00 |
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| Species: | Cupiennius salei (Wandering spider) [6928] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: KDDKNCIPKH HECTNDKKNC CKKGLTKMKC KCFTVADAKG ATSERCACDS SLLQKFGFTG
61: LHIIKGLF