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8.B.19.2.4
Ω Lsp-IA (47aas) Ca2+ channel inhibitor

Accession Number:P85079
Protein Name:Ω Lsp-IA
Length:87
Molecular Weight:10298.00
Species:Geolycosa sp. (strain A267TDLS2-KZARNA) (Wolf spider) (Lycosa kazakhstanicus) [420151]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Pfam: PF10530   

Gene Ontology

GO:0005576 C:extracellular region
GO:0019855 F:calcium channel inhibitor activity
GO:0009405 P:pathogenesis

References (2)

[1] “Omega-Lsp-IA, a novel modulator of P-type Ca(2+) channels.”  Pluzhnikov K.A.et.al.   17888477
[2] “Novel spider toxin slows down the activation kinetics of P-type Ca2+ channels in Purkinje neurons of rat.”  Fisyunov A.et.al.   15590128

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKLSIFFVLF FIAIAYCQPE FLDDEEDEVE ETLPVAEEGR EKSCITWRNS CMHNDKGCCF 
61:	PWSCVCWSQT VSRNSSRKEK KCQCRLW