8.B.19.2.7 DELTA-miturgitoxin-Cp1b of 183 aas and 1 N-terminal TMS. It is a spider venom toxin that exhibits cytolytic activity by forming an α-helix across the membrane and is lethal to insect larvae (Vassilevski et al. 2010, Sachkova et al. 2014). It causes instant paralysis and death to larvae of the flesh fly
(S. carnaria) at doses of 20 µg/g, and at doses of less than 10 µg/g, it causes
reversible paralysis by causing stable and irreversible depolarization of fly muscle fibers while destabilizing the membrane (Vassilevski et al. 2010).
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Accession Number: | C0HKG8 |
Protein Name: | DELTA-miturgitoxin-Cp1b |
Length: | 183 |
Molecular Weight: | 20819.00 |
Species: | Cheiracanthium punctorium (Yellow sac spider) [682790] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
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1: MKFSLFFSVF FLAVLHACLS ESEIDLEDEE HFMSSDSFLS EIQDESRGKT CIERNKECTN
61: DRHGCCRGKI FKDKCTCVKN GKTEKCVCTQ KKWAKIIESY IGDIPALPKP VDDKCVPKHA
121: DCSKRKDECC KGGIFKYQCK CYDMYDDDGE KTDLCGCVSP VEHQAIEGAL RIAKKLIGDR
181: WGR