8.B.32.1.13 Conotoxin BuIA of 60 aas and 2 TMSs, N- and C-terminal. Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them (Shiembob et al. 2006). alpha3beta2 nAChR neuronal nicotinic acetylcholine receptors (nAChRs) are pentamers composed of alpha and beta subunits.
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Accession Number: | P69657 |
Protein Name: | Alpha-conotoxin BuIA |
Length: | 60 |
Molecular Weight: | 6394.00 |
Species: | Conus bullatus (Bubble cone) [89438] |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
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1: MFTVFLLVVL TTTVVSFPSD RASDGRNAAA NDKASDVVTL VLKGCCSTPP CAVLYCGRRR