8.B.40.1.1 Con-ikot-ikot conotoxin of 123 aas and 1 N-terminal TMS. It exists as a dimer and inhibits AMPA receptor desensitization (Walker et al. 2009) and possibly ionotropic glutamate receptors (Robinson and Norton 2014).
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Accession Number: | P0CB20 |
Protein Name: | Con-ikot-ikot |
Length: | 123 |
Molecular Weight: | 13635.00 |
Species: | Conus striatus (Striated cone) [6493] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
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1: MAMNMSMTLC MFVMVVVAAT VIDSTQLQEP DLSRMRRSGP ADCCRMKECC TDRVNECLQR
61: YSGREDKFVS FCYQEATVTC GSFNEIVGCC YGYQMCMIRV VKPNSLSGAH EACKTVSCGN
121: PCA