TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


9.A.14.1.11
G-protein coupled receptor 161, Gpr161 of 529 aas.  Key negative regulator of Shh signaling and the sonic hedgehog pathway via cAMP signaling.  Shh signalling promotes the processing of GLI3 into GLI3R during neural tube development (Mukhopadhyay et al. 2013).

Accession Number:Q8N6U8
Protein Name:G-protein coupled receptor 161
Length:529
Molecular Weight:58559.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell projection1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MSLNSSLSCR KELSNLTEEE GGEGGVIITQ FIAIIVITIF VCLGNLVIVV TLYKKSYLLT 
61:	LSNKFVFSLT LSNFLLSVLV LPFVVTSSIR REWIFGVVWC NFSALLYLLI SSASMLTLGV 
121:	IAIDRYYAVL YPMVYPMKIT GNRAVMALVY IWLHSLIGCL PPLFGWSSVE FDEFKWMCVA 
181:	AWHREPGYTA FWQIWCALFP FLVMLVCYGF IFRVARVKAR KVHCGTVVIV EEDAQRTGRK 
241:	NSSTSTSSSG SRRNAFQGVV YSANQCKALI TILVVLGAFM VTWGPYMVVI ASEALWGKSS 
301:	VSPSLETWAT WLSFASAVCH PLIYGLWNKT VRKELLGMCF GDRYYREPFV QRQRTSRLFS 
361:	ISNRITDLGL SPHLTALMAG GQPLGHSSST GDTGFSCSQD SGTDMMLLED YTSDDNPPSH 
421:	CTCPPKRRSS VTFEDEVEQI KEAAKNSILH VKAEVHKSLD SYAASLAKAI EAEAKINLFG 
481:	EEALPGVLVT ARTVPGGGFG GRRGSRTLVS QRLQLQSIEE GDVLAAEQR