9.A.14.13.45
GPR4 of 362 aas and 7 TMSs. It is a proton-sensing G-protein coupled receptor that couples to multiple intracellular signaling pathways (Chen et al. 2011). It could potentially be used as therapeutic targets and diagnostic biomarkers for the development of novel broad spectrum therapeutic agents (Jia et al. 2023).
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| Accession Number: | P46093 |
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| Protein Name: | G-protein coupled receptor 4 |
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| Length: | 362 |
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| Molecular Weight: | 40982.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 7 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MGNHTWEGCH VDSRVDHLFP PSLYIFVIGV GLPTNCLALW AAYRQVQQRN ELGVYLMNLS
61: IADLLYICTL PLWVDYFLHH DNWIHGPGSC KLFGFIFYTN IYISIAFLCC ISVDRYLAVA
121: HPLRFARLRR VKTAVAVSSV VWATELGANS APLFHDELFR DRYNHTFCFE KFPMEGWVAW
181: MNLYRVFVGF LFPWALMLLS YRGILRAVRG SVSTERQEKA KIKRLALSLI AIVLVCFAPY
241: HVLLLSRSAI YLGRPWDCGF EERVFSAYHS SLAFTSLNCV ADPILYCLVN EGARSDVAKA
301: LHNLLRFLAS DKPQEMANAS LTLETPLTSK RNSTAKAMTG SWAATPPSQG DQVQLKMLPP
361: AQ