9.A.14.13.46 P2Y purinoceptor 14, P2RY14, of 338 aas and 7 TMSs, a drug target for inflammation and immune responses. The mode of activation of purinergic receptors and insight into the carbohydrate drug development for GPCRs have been examined (Zhao et al. 2023).
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Accession Number: | Q15391 |
Protein Name: | P2Y purinoceptor 14 |
Length: | 338 |
Molecular Weight: | 38971.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MINSTSTQPP DESCSQNLLI TQQIIPVLYC MVFIAGILLN GVSGWIFFYV PSSKSFIIYL
61: KNIVIADFVM SLTFPFKILG DSGLGPWQLN VFVCRVSAVL FYVNMYVSIV FFGLISFDRY
121: YKIVKPLWTS FIQSVSYSKL LSVIVWMLML LLAVPNIILT NQSVREVTQI KCIELKSELG
181: RKWHKASNYI FVAIFWIVFL LLIVFYTAIT KKIFKSHLKS SRNSTSVKKK SSRNIFSIVF
241: VFFVCFVPYH IARIPYTKSQ TEAHYSCQSK EILRYMKEFT LLLSAANVCL DPIIYFFLCQ
301: PFREILCKKL HIPLKAQNDL DISRIKRGNT TLESTDTL