9.A.14.13.50
Pentatricopeptide repeat-containing protein OGR1, mitochondrial, of 587 aas and 2 or more TMSs. It is involved in multiple site RNA editing events in mitochondria, and is essential
for C-to-U RNA editing at seven specific sites of nad2, nad4, cox2,
cox3 and ccmC transcripts, all coding for proteins involved in the
mitochondrial electron transport chain coupled to ATP generation. It is required for normal growth and development (Kim et al. 2009). Functional expression of the proton sensors ASIC1a, TMEM206, and OGR1 together with BKCa channels is associated with cell volume changes and cell death (Pissas et al. 2024).
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| Accession Number: | B8YEK4 |
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| Protein Name: | Pentatricopeptide repeat-containing protein OGR1, mitochondrial |
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| Length: | 587 |
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| Molecular Weight: | 64618.00 |
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| Species: | Oryza sativa subsp. japonica (Rice) [39947] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion1 |
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| Substrate |
hydron |
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1: MSVSAAARHL ESLLPRLASL RHYLQFHARL LTSGHLGAHP GLRARFLDRL ALSPHPAALP
61: HALLLLRSLP TPATNDLNAA LRGLAASPHP ARSLLLLAGR LLPALLPRPD ALSLSFALKA
121: SARCSDAHTT VQLHALVLRL GVAADVRLLT TLLDSYAKCG DLASARKVFD EMTVRDVATW
181: NSLLAGLAQG TEPNLALALF HRLANSFQEL PSREEPNEVT IVAALSACAQ IGLLKDGMYV
241: HEFAKRFGLD RNVRVCNSLI DMYSKCGSLS RALDVFHSIK PEDQTLVSYN AAIQAHSMHG
301: HGGDALRLFD EMPTRIEPDG VTYLAVLCGC NHSGLVDDGL RVFNSMRVAP NMKHYGTIVD
361: LLGRAGRLTE AYDTVISMPF PADIVLWQTL LGAAKMHGVV ELAELAANKL AELGSNVDGD
421: YVLLSNVYAS KARWMDVGRV RDTMRSNDVR KVPGFSYTEI DGVMHKFING DKEHPRWQEI
481: YRALEDIVSR ISELGYEPET SNVLHDIGEE EKQYALCYHS EKLAIAFGLI ATPPGETLRV
541: IKNLRICGDC HVVAKLISKA YGRVIVIRDR ARFHRFEDGQ CSCRDYW