9.A.14.15.4
Metabolomic GABAB receptor (GABABR, GPR156, GABABL, PGR28) of 814 aas and 7 N-terminal TMSs in a 4 + 3 TMS arrangement. It plays a role in idiopathic pulmonary fibrosis (IPF), a rare persistent lung disorder that actuates scarring of lung tissues, making breathing difficult (Mishra et al. 2021).
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| Accession Number: | Q8NFN8 |
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| Protein Name: | Probable G-protein coupled receptor 156 |
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| Length: | 814 |
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| Molecular Weight: | 89097.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 7 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MEPEINCSEL CDSFPGQELD RRPLHDLCKT TITSSHHSSK TISSLSPVLL GIVWTFLSCG
61: LLLILFFLAF TIHCRKNRIV KMSSPNLNIV TLLGSCLTYS SAYLFGIQDV LVGSSMETLI
121: QTRLSMLCIG TSLVFGPILG KSWRLYKVFT QRVPDKRVII KDLQLLGLVA ALLMADVILL
181: MTWVLTDPIQ CLQILSVSMT VTGKDVSCTS TSTHFCASRY SDVWIALIWG CKGLLLLYGA
241: YLAGLTGHVS SPPVNQSLTI MVGVNLLVLA AGLLFVVTRY LHSWPNLVFG LTSGGIFVCT
301: TTINCFIFIP QLKQWKAFEE ENQTIRRMAK YFSTPNKSFH TQYGEEENCH PRGEKSSMER
361: LLTEKNAVIE SLQEQVNNAK EKIVRLMSAE CTYDLPEGAA PPASSPNKDV QAVASVHTLA
421: AAQGPSGHLS DFQNDPGMAA RDSQCTSGPS SYAQSLEGPG KDSSFSPGKE EKISDSKDFS
481: DHLDSGCSQK PWTEQSLGPE RGDQVPMNPS QSLLPERGGS DPQRQRHLEN SEEPPERRSR
541: VSSVIREKLQ EVLQDLGLGP EASLSTAPSC HQQTWKNSAA FSPQKMPLSK ELGFSPYMVR
601: RRRAAQRARS HFPGSAPSSV GHRANRTVPG AHSRLHVQNG DSPSLAPQTT DSRVRRPSSR
661: KPSLPSDPQD RPGTLEGSKQ SQTEPEGARG SKAAFLRQPS GSGRAPSPAA PCLSKASPDL
721: PEQWQLWPPV PSGCASLSSQ HSYFDTESSS SDEFFCRCHR PYCEICFQSS SDSSDSGTSD
781: TDPEPTGGLA SWEKLWARSK PIVNFKDDLK PTLV