9.A.14.3.20
Octopamine Receptor, OamB, of 645 aas and 7 TMSs. It is a receptor for octopamine (OA) which is a neurotransmitter, neurohormone and neuromodulator in invertebrates (Han et al. 1998).
It stimulates intracellular accumulation of cAMP and Ca2+ following ligand binding (Balfanz et al. 2005). Leads to breakdown of the posterior follicle wall, resulting in ovulation (Deady and Sun 2015). Also plays a role in social behavior by modulating male agression (Luo et al. 2014).
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| Accession Number: | Q7JQF1 |
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| Protein Name: | Octopamine receptor Oamb |
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| Length: | 645 |
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| Molecular Weight: | 71702.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Number of TMSs: | 7 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MNETECEDLI KSVKWTEPAN LISLAVLEFI NVLVIGGNCL VIAAVFCSNK LRSVTNFFIV
61: NLAVADLLVG LAVLPFSATW EVFKVWIFGD LWCRIWLAVD VWMCTASILN LCAISLDRYV
121: AVTRPVTYPS IMSTKKAKSL IAGIWVLSFF ICFPPLVGWK DQKAVIQPTY PKGNHTLYYT
181: TTMSSSEDGQ LGLDSIKDQG EASLPPSPPH IGNGNAYNPY DPGFAPIDGS AEIRIAAIDS
241: TSTSTTATTT TTASSSSTTE TEMDLDLLNA PPQNRPQTIS GSCPWKCELT NDRGYVLYSA
301: LGSFYIPMFV MLFFYWRIYR AAVRTTRAIN QGFKTTKGSK GIGSRFEEQR LTLRIHRGRG
361: SNQQDSMHSN GSTQSTTTTL GTPSPERLSK YATRRLHHHD KIKISVSYPS SENISELAGH
421: GDVGHERRQS GNALFAVHYN GTNGRESTES QLYRQQQQHG VASSCYLQVG KGLPELARRQ
481: SNTSEAGGSG HSRPANKKMG RRNIKAQVKR FRMETKAAKT LAIIVGMFIF CWCPFFTMYI
541: IRPFCQDCVD PLLFSVLFWL GYCNSAVNPM IYALFSKDFR FAFKRIICRC FCSRQSVSLK
601: SSRRGSDMSA IRIRARTPSI TPSAAAHSFG DESELHHSEM SNDPR