TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.A.54.1.1









Probable lysosomal cobalamin exporter, NESI or C61F disease protein; defective in cobalamin F type disease (540aas; 9 TMSs in a 5 + 4 arrangement) (Ruivo et al., 2009; Rutsch et al., 2009; Gailus et al., 2010; Wilcken, 2012) (also called LMBR1 domain-containing protein; liver regeneration p53-related protein, Lipocalin-interacting membrane receptor, limb region 1 protein, etc.) Homologues are present in all eukaryotes and probably some bacteria (e.g., EcsB protein of Bacillus cereus (gi#47570159; 10 TMSs; distantly related to 3.A.1.128.2). RodA of E. coli (9.B.3.1.2) may also be distantly related.

Eukaryota
Metazoa
NESI of Homo sapiens (Q9NUN5)
9.A.54.1.2









Probable lysosomal cobalamin transporter of 646 aas and 7 TMSs in a 5 + 2 + hydrophilic domain arrangement.

Eukaryota
Fungi
CHGG_01714 of Chaetomium globosum
9.A.54.1.3









Probable lysosomal cobalamine exporter of 590 aas and 9 putative TMSs.

Eukaryota
Fungi
Cobalamine exporter of Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)
9.A.54.1.4









Conserved plant hypothetical protein (9 TMSs)

Eukaryota
Viridiplantae
Hypothetical protein of Ricinus communis (B9SQ26)
9.A.54.1.5









Uncharacterized protein of 476 aas and 9 TMSs in a 5 + 4 arrangement.

Eukaryota
Kinetoplastida
UP of Trypanosoma cruzi
9.A.54.2.1









Hypothetical alveolata protein conserved in Plasmodium species, of 585 aas and 9 TMSs in a 5 + 4 arrangement).

Eukaryota
Apicomplexa
Hypothetical protein of Plasmodium knowlesi (B3L7M4)

 
9.A.54.3.1









LMBR1-like conserved protein of 612 aas and 9 TMSs in a 5 + 4 TMS arrangement.

Eukaryota
Intramacronucleata
LMBR1-like protein of Tetrahymena thermophila (Q22WA5)
9.A.54.3.2









Uncharacterized protein of 609 aas and 9 TMSs in a 5 + 4 TMS arrangement.

Eukaryota
Fungi
UP of Torulaspora delbrueckii (Candida colliculosa)
9.A.54.3.3









Uncharacterized protein of 741 aas and 9 or 10 TMSs in a 5 + 4 or 5 TMS.

Eukaryota
Bangiophyceae
UP of Cyanidioschyzon merolae
9.A.54.3.4









LMBR1 protein homologue of 537 aas

Eukaryota
Viridiplantae
LMBR1 homologue of Ostreococcus tauri