| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
9.B.12.1.1 | Salt-stress and cold-shock-induced hydrophobic peptide, BLT101 or ESI3 | Eukaryota |
Viridiplantae, Streptophyta | BLT101 of Lophopyrum elongatum (P68178) |
|
9.B.12.1.2 | Membrane peptide of 55 aas, plasma membrane proteolipid 3, Pmp3/Sna1. Plays a role in the regulation of membrane potential, possible by mediating a proton leak (Navarre and Goffeau 2000). | Eukaryota |
Fungi, Ascomycota | Pmp3p of Saccharomyces cerevisiae (P87284) |
|
9.B.12.1.3 | Pmp3 family (UPF0057) member of 87 aas. | Bacteria |
Bacillota | Pmp3 family member of Bacillus anthracis |
|
9.B.12.1.4 | Pmp3 famiy member of 56 aas | Bacteria |
Bacillota | Pmp3 family member of Bacillus subtilis |
|
9.B.12.1.5 | Ric1 of 58 aas | Bacteria |
Chlorobiota | Ric1 of Chlorobaculum parvum |
|
9.B.12.1.6 | hydrophobic peptide of 54 aas and 2 TMSs, RCI2A or LTI6A. It is upregulated upon drought/salt stress (Kwok et al. 2020). It might oligomerized to form a proton channel but this hypothesis has not been tested. | Eukaryota |
Viridiplantae, Streptophyta | RCI2A of Arabidopsis thaliana (thale cress) |
|
9.B.12.2.1 | Uncharacterized ORF, YqaE, of 52 aas and 2 putative TMSs. The eukaryotic homologues functionally suppress the conditional growth defects in bacterial deletion mutant, demonstrating the conserved cross-kingdom membrane functions by PMP3(i)hs. There is a direct reciprocal relationship between PMP3(i)hs expression and Vm differentials in both prokaryotic and eukaryotic cells. Cumulative with the PMP3(i)hs ubiquitous abundance, their lipid-binding selectivities and membrane protein colocalization, it is a key element in membrane homeostasis (Kwok et al. 2020). | Bacteria |
Pseudomonadota | YqaE of E. coli (P0AE42) |
|
9.B.12.2.2 | Plasma membrane proteolipid 3, Pmp3 of 57 aas | Eukaryota |
Fungi, Mucoromycota | Pmp3 of Rhizobus delemar |
|
9.B.12.3.1 | Uncharacterized ORF, Sna3 (YJL151c). Targeting to the endosomal pathway depends on its interaction with Rsp5p, and multivesicular body sorting depends on ubiquitylation (Stawiecka-Mirota et al. 2007). | Eukaryota |
Fungi, Ascomycota | Sna3 of Saccharomyces cerevisiae |
|
9.B.12.3.2 | Vacuolar Sna4 of 140 aas with two N-terminal TMSs. It is transported to the vauolar membrane via the alkaline phosphatase (ALP) pathway which bypasses the multivesicular bodies (MVBs) (Pokrzywa et al. 2009). | Eukaryota |
Fungi, Ascomycota | Sna4 of Saccharomyces cerevisiae |
|
9.B.12.3.3 | Sna2 of 79 aas. Two tyroline-based sorting motifs are required for proper ER exit and vacuolar targeting (Renard et al. 2010). | Eukaryota |
Fungi, Ascomycota | Sna2 of Sacchaomyces cerevisiae |
|
9.B.12.4.1 | Uncharacterized ORF, F47B7.1 | Eukaryota |
Metazoa, Nematoda | F47B7.1 of Caenorhabditis elegans |