TCDB is operated by the Saier Lab Bioinformatics Group

9.B.18 The Xanthan Glycosyl Transferase, GumD (GumD) Family

The GumD family cosists of a large number of glycosyltransferases involved in exo-polysaccharide biosynthesis and export.  GumD of Xanthomonas campestris is a costituent of a multicomponent system involved in the biosynthesis and export to the cell surface.  Some of the constituents of this system include GumB (TC# 1.B.18.3.7) and GumC (TC#8.A.3.1.3) (Bianco et al. 2014).  The N-terminus of GumD (residues 30 - 140) consists of a domain of closely packed 4 TMSs, followed by a hydrophilic domain that includes 1 or 2 additional TMSs.  Residues 75 - 275 consist of the NADB_Rossmann or CoA binding_3 domain, while residues 300 to the end consist of the Bacterial Transferase (bac_transf) domain of CDD. 

References associated with 9.B.18 family:

Bianco, M.I., M. Jacobs, S.R. Salinas, A.G. Salvay, M.V. Ielmini, and L. Ielpi. (2014). Biophysical characterization of the outer membrane polysaccharide export protein and the polysaccharide co-polymerase protein from Xanthomonas campestris. Protein Expr Purif 101: 42-53. 24927643
Pérez-Burgos, M., I. García-Romero, J. Jung, E. Schander, M.A. Valvano, and L. Søgaard-Andersen. (2020). Characterization of the Exopolysaccharide Biosynthesis Pathway in Myxococcus xanthus. J. Bacteriol. 202:. 32778557