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9.B.188.1.3
The transmembrane (2 TMSs, N- and C-termini) Emp24 domain-containing protein 3, TMED3 of 217 aas. TMED3 plays a role in esophageal carcinomas (Kattner 2023). It has a potential role in vesicular protein trafficking, mainly in the early secretory pathway, and it contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network (Emery et al. 2000). It may regulate the progression of breast cancer (Yang et al. 2023).

Accession Number:Q9Y3Q3
Protein Name:Transmembrane emp24 domain-containing protein 3
Length:217
Molecular Weight:24777.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Endoplasmic reticulum-Golgi intermediate compartment membrane1 / Single-pass type I membrane protein2
Substrate

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FASTA formatted sequence
1:	MGSTVPRSAS VLLLLLLLRR AEQPCGAELT FELPDNAKQC FHEEVEQGVK FSLDYQVITG 
61:	GHYDVDCYVE DPQGNTIYRE TKKQYDSFTY RAEVKGVYQF CFSNEFSTFS HKTVYFDFQV 
121:	GDEPPILPDM GNRVTALTQM ESACVTIHEA LKTVIDSQTH YRLREAQDRA RAEDLNSRVS 
181:	YWSVGETIAL FVVSFSQVLL LKSFFTEKRP ISRAVHS