9.B.188.1.8
Transmembrane emp24 domain-containing protein 7, TMED7, of 224 aas and 2 TMSs, N- and C-terminal. It plays a role in vesicular protein trafficking, mainly in
the early secretory pathway. It appears to function in the biosynthesis
of secreted cargo including processing and post-translational
modifications and thereby in embyogenesis (Nie et al. 2020).
|
| Accession Number: | Q9Y3B3 |
|---|
| Protein Name: | Transmembrane emp24 domain-containing protein 7 |
|---|
| Length: | 224 |
|---|
| Molecular Weight: | 25172.00 |
|---|
| Species: | Homo sapiens (Human) [9606] |
|---|
| Number of TMSs: | 2 |
|---|
| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Single-pass type I membrane protein2 |
|---|
| Substrate |
|
|---|
1: MPRPGSAQRW AAVAGRWGCR LLALLLLVPG PGGASEITFE LPDNAKQCFY EDIAQGTKCT
61: LEFQVITGGH YDVDCRLEDP DGKVLYKEMK KQYDSFTFTA SKNGTYKFCF SNEFSTFTHK
121: TVYFDFQVGE DPPLFPSENR VSALTQMESA CVSIHEALKS VIDYQTHFRL REAQGRSRAE
181: DLNTRVAYWS VGEALILLVV SIGQVFLLKS FFSDKRTTTT RVGS