9.B.313.1.7
PTH11 receptor of 628 aas and 7 TMSs. It is required for pathogenicity. PTH11 has an amino-terminal extracellular cysteine-rich EGF-like domain (CFEM domain), a characteristic also seen in human GPCRs. Sixty-one PTH11-related proteins were identified in M. grisea that share a common domain with homologs in Neurospora crassa and other fungi belonging to this sub-phylum of the Ascomycota (the Pezizomycotina). None was detected in other fungal groups (Basidiomycota or other Ascomycota subphyla, including yeasts) or any other eukaryote. These proteins were suggested to be GPCRs (Kulkarni et al. 2005).
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| Accession Number: | Q9Y786 |
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| Protein Name: | Integral membrane protein |
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| Length: | 628 |
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| Molecular Weight: | 69034.00 |
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| Species: | Magnaporthe grisea (Crabgrass-specific blast fungus) [148305] |
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| Number of TMSs: | 7 |
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| Substrate |
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1: MVAFTRFLLS SAVLIWGAAS VQVPQQTLID IVTKTPSCAM KCFTDAITSR NCSLESAQLV
61: ADCICVSNPT LSTAATCVQK SCKFSEQLVA RNLTLFSLCK DYPMENRSAD VINIAIIGFV
121: VTVPVVVIRI LSRLYSSGRL WWDDYTCLVA SVFLFGMLGM EIESSRLGFG IHIWVIEEAP
181: GLSLLKYFWV GQMMYIVVQV FAKISILILY IRLFTTPWFQ MFCKCSMVFM GLHGVGYLVL
241: VIFQCTPVAA VYNRQIQGMC IDFNPIVYSG AALSVFEDVV LVVIPIPELW SLRLNFKKKM
301: GLMLMFAIGL VATVTSIIRI NYLVKIGFTY DQSWDNVDPI TWSVIEEFCA IICGSLPSCR
361: AIVNAWIPRI WSSVDHSDVG NSLDVQRDNA FARSEKALGG APQTARRNRF SLYRLTTEID
421: PLDLDFRQSG GRWKSCASAV GMDSEEGLGK VEEMSICSDT KRASEGLKRR TEVGASPGGP
481: DMVSVPIHSP GEVIEMSRRA STSVLHQSVA ETLFRYSMAP STRSNRSYSV IGTAWVAPDA
541: TVEGGVSHKA LAWDIPAVPD LPTDKIVWPL PSSLETSVEA EAEFSGPIRE RLASDGSINT
601: DLGSEAEEKS DFMGSARNSR QGLPGGLI