TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.325.1.1









The putative two component ABC-4-type transporter (Rafii and Park, 2008).  It appears to transport multiple drugs including ethidium and fluoroquinolones. The membrane protein (Q83XH0) is N-terminally truncked and is missing 88 aas.  A full length protein is R5TMA6 with 451 aas and 10 TMSs in a 5 + 5 TMS arrangement. This membrane protein has replaced the former one in this TC entry.

Bacteria
Bacillota
The ABC-4 M/C-C transporter of Clostridium hathewayi (Q83XH0)
(Q83XH1)
9.B.325.1.2









Putative transporter of 564 aas and 11 TMSs in a 1 + 5 + 5 TMS topology. Each of the 5 TMS domains appears to have a 3 + 2 TMS arrangment.  This protein hits proteins 9.B.28.2.6 and 2.7 in a TC BLAST search, which are DUF975/UPF6259 family proteins, with decent scores (e-10 and e-6, respectively). It is the first half of the 9.B.325.1.2 protein that resembles proteins of TC family 9.B.28 (particularly 9.B.325.2.6 and 7). This is the only member of family 9.B.325 that has this domain, and only its second 5 TMS domain is homolgous to other members of 9.B.325. Other 10 TMS members of the 9.B.325 family have two copies of the 5 TMS repeat unit. The N-terminal 5 TMS domain in protein 9.B.325.1.2 may be a protease domain that processes the transporter domain (see family 9.B.28 description).

Bacteria
Bacillota
Putative transporter of an uncultured Butyricicoccus sp.
9.B.325.1.3









Uncharacterized protein of 253 aas and 5 TMSs.

Bacteria
Spirochaetota
UP of Oceanispirochaeta sp. M1
9.B.325.1.4









Uncharacterized protein of 216 aas and 5 TMSs.

Bacteria
Bacillota
UP of Candidatus Borkfalki ceftriaxensis
9.B.325.1.5









Uncharacterized protein of 427 aas and 10 TMSs in a 5 + 5 TMS arrangement, where each of the two putative repeat units has a 3 + 2 TMS arrangement.

Bacteria
Bacillota
UP of Eubacterium sp. CAG:161
9.B.325.1.6









Uncharacterized protein of 436 aas and 10 TMSs in a 5 + 5 TMS arrangement where each 5 TMS domain has a 3 + 2 TMS arrangement.

Bacteria
Bacillota
UP of Bacteroides pectinophilus
9.B.325.1.7









Uncharacterized protein of 288 aas and 5 TMSs in a 3 + 3 TMS arrangement.

Bacteria
Actinomycetota
UP of Bifidobacterium animalis
9.B.325.1.8









Uncharacterized protein with 10 TMSs in a 5 + 5 TMS arrangement.  Its gene is adjacent to one encoding an ABC exporter (TC# 3.A.1.111.8), and could be a chaparone protein for insertion and folding of the ABC transporter (see also TC# 9.B.29.2.17 which appears to be a chaparone protein for the ABC exporter with TC# 3.A.1.122.2).

Bacteria
Bacillota
UP of Lachnospiraceae bacterium