9.B.325.1.2
Putative transporter of 564 aas and 11 TMSs in a 1 + 5 + 5 TMS topology. Each of the 5 TMS domains appears to have a 3 + 2 TMS arrangment. This protein hits proteins 9.B.28.2.6 and 2.7 in a TC BLAST search, which are DUF975/UPF6259 family proteins, with decent scores (e-10 and e-6, respectively). It is the first half of the 9.B.325.1.2 protein that resembles proteins of TC family 9.B.28 (particularly 9.B.325.2.6 and 7). This is the only member of family 9.B.325 that has this domain, and only its second 5 TMS domain is homolgous to other members of 9.B.325. Other 10 TMS members of the 9.B.325 family have two copies of the 5 TMS repeat unit. The N-terminal 5 TMS domain in protein 9.B.325.1.2 may be a protease domain that processes the transporter domain (see family 9.B.28 description).
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| Accession Number: | SCJ14563 |
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| Protein Name: | SCJ14563.1 Predicted membrane protein [uncultured Butyricicoccus sp.] |
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| Length: | 565 |
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| Molecular Weight: | |
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| Species: | uncultured Butyricicoccus sp. [1193532] |
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| Number of TMSs: | 11 |
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| Substrate |
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1: MWQRKELKRR GKRQFLRNWA ATVAVCFILA FTGAEFAGSA DFIGQFDPSA MLPDDQVAIQ
61: AVSLSNWELL LEWLRIDPMD GTHPMWAAAD QSLAPAFDTL TAPFSAFFAL LERSRFAGWL
121: DIALAALGIA GGLWFTIWVL SAVSVGARRF LLESRVRDNI SIAAMFTPFQ HGCWRNVAKG
181: MFLRSLFLLL WACTIVGFPV KLYSYRMVPY ILAENPQARP AETLRLSRQM MRGNKWRCFV
241: LDLTFYLHWT FLPLLASTVL GTAIGLATGD VALCQSLAAA AAGLLSLLFV NGYRSATDAG
301: LYAALRQAQL DAGTPLSALF VVPAFGETAP AGEKPRLPDA DVRLPEDPVF HYAQRHKLDY
361: NRHYGLRTLI LLFFTFAFIG WVWEVALHIV TKGMFVNRGT MLGPWLPIYG AGGALVLLLL
421: KKLFTRPVAT FLVSMVLCSV IEYFSSWYLE VTKGIRWWDY SGYFMNLNGR ICLEGAVIFG
481: LGCCAVVYFA GPLLGGLLDR LSPARQNTLC AVLLTLFVAD LAYSHFHPNA GEGITDYNDW
541: QQDAARDALL PEAANDSVTA ILSE