| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
9.B.360.1.1 | TMEM187 of 261 aas and 7 TMSs. The Q236H variant is near the C-terminus. Like SYTL4 (TC# 9.A.57.1.8), the TMEM187 gene is expressed in the brain and interacts with four known Autism spectrum disorder ASD genes, namely, HCFC1; TMLHE; MECP2; and GPHN. TMM187 is in linkage with MECP2, which is a well-known determinant of brain structure and size and is an autism gene. Other members of the TMEM gene family, TMEM132E and TMEM132D genes are associated with bipolar and panic disorders, respectively, while TMEM231 is a known syndromic autism gene (Rafi et al. 2019). | Eukaryota |
Metazoa, Chordata | TMEM187 of Homo sapiens |
|
9.B.360.1.2 | Uncharacterized protein of 260 aas and 8 TMSs. | Eukaryota |
Metazoa, Chordata | UP of Ciona intestinalis |
|
9.B.360.1.3 | Uncharacterized protein of 214 aas and 4 - 6 TMSs. | Eukaryota |
Metazoa, Cnidaria | UP of Pocillopora damicornis |
|
9.B.360.1.4 | Uncharacterized protein of 121 aas and 2 TMSs. This might be a C-terminally truncated protein. | Eukaryota |
Metazoa, Echinodermata | UP of Apostichopus japonicus |
|
9.B.360.1.5 | Uncharacterized protein of 280 aas with 4 N-terminal TMSs. | Eukaryota |
Metazoa, Priapulida | UP of Priapulus caudatus |
|
9.B.360.1.6 | Uncharacterized protein of 310 aas and 7 (or 8) TMSs | Eukaryota |
UP of Capsaspora owczarzaki | |
|
9.B.360.1.7 | TMEM187 protein with 182 aas and 4 TMSs. | Eukaryota |
Metazoa, Chordata | TMEM187 protein of Cynoglossus semilaevis |
|
9.B.360.1.8 | Transmembrane protein 187-like of 164 aas and 4 TM | Eukaryota |
Metazoa, Cnidaria | TMEM187 of Acropora digitifera |